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m6A（N6-甲基腺苷）是哺乳動(dòng)物 mRNA 中豐富的內(nèi)部修飾。這種修飾由 m6A 甲基轉(zhuǎn)移酶或稱 “寫手"（如 METTL3 和 METTL14）完成，并可由作為 “擦除器 "的去甲基化酶（如 FTO 和 ALKBH5）逆轉(zhuǎn)。m6A 修飾的 mRNA 的穩(wěn)定性受 m6A 閱讀蛋白 YTHDFs 的調(diào)節(jié)，YTHDFs 可識別 m6A 并降低目標(biāo)轉(zhuǎn)錄本的穩(wěn)定性。
targets m6A in WB, IHC, IF, IP, RIP, Dot Blot, ELISA applications and shows reactivity with m6A, Human, Mouse, Rat samples.
| Tested Applications | RIP, IHC, ELISA, Dot Blot Application Description |
| Cited Applications | WB, IHC, IF, IP, RIP |
| Tested Reactivity | m6A, Human, Mouse, Rat |
| Cited Reactivity | human, mouse, rat, pig, monkey |
| Immunogen | Compound |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | m6A |
| Synonyms | 6-N-Methyladenoside, m6A, N6-methyladenosine |
| GenBank Accession Number | m6A |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_2918796 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
| 貨號 | 品名 | 規(guī)格 | 品牌 |
| 78DA10019 | m6A Monoclonal antibody | 50 µL | BIOHUB |
